Ohio State opens as the preseason No. 1 team at home against Ball State on Saturday, with quarterback Julian Sayin coming off a 2025 season of 3,610 passing yards and 32 touchdowns.

Ohio State posted the highest completion rate in the country last year at 76.7%, while Ball State finished with the fewest total yards in Division I at 2,551. Ohio State is a 50.5-point favorite at DraftKings, with the total set at 56.5. Ball State is still climbing out of the MAC's lower tier in coach Mike Uremovich's second year, and Mizzell gives the offense real juice at quarterback. He threw for 2,889 yards and 26 touchdowns a season ago at Division II Concord, with five games of 300 passing yards or more, the kind of volume production that earned him a shot at the FBS level. Ohio State's defense is replacing key pieces after last year's championship run, but this is still a massive step up in competition for Mizzell in his first game above Division II. How he handles that jump will say plenty about whether his production translates.
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